Megaloblastic anemia | Dr Anutosh Chakraborty

Megaloblastic Anemia


Definition [Expert Homeopathy]
Addisonian pernicious anemia: Due to failure in secretion of intrinsic factor by the stomach, responsible for Vit. B12 absorption other than surgery. It is mainly due to Vit. B12 and Folic acid deficiency...


Etiology / Causation
Nutritional: Diet deficient in B12 and folate in vegetarians, infants fed on goat milk or by anemic mothers.
Defective absorption
Tropical spruce
Idiopathic steatorrhea
Gluten-enteriopathy
Short-circuiting of small intestine
Bland or stagnated loop of small intestine contains bacteria which consumes Vit. B12
Lactation, growing children especially vegetarians
Infancy
Associated with hemolytic anemia
Associated with anticonvulsant therapy
Worms infestation e.g. fish tape worm


Symptoms / Signs
General features of anemia like: weakness, lassitude, pallor, palpitation etc.
Intermittent soreness of tongue with ulcers and rawness
Periodic diarrhea and abdominal pain
Loss of weight
Skin and mucous membrane pale
In severe cases, they become lemon-yellow colored
Later on, mucous membrane of mouth becomes smooth and atrophic
Psychic symptoms: Lassitude, lack of interest in surroundings, depressive psychosis, mania
Neurological: Tenderness of calf muscles, ataxia, spasticity, nystagmus
In Children: mental retardation, tremors
Hyperpigmentation of skin: specially on dorsum of hands, toes. Formation of dark bands over interphalangeal joints, patches on palms and soles tongue, face etc.
Subacute combined degeneration of cord(SACS): absent knee-jerk with up going planters due to polyneuropathy and corticospinal tract involvement...


Investigations
Blood picture
  • Macrocytic anemia
  • M.C.V increased
  • Thrombocytopenia
  • Serum B12 level is low
Urine examination: Increased urobilinogen
Gastric analysis: Achlorhydria
Bone marrow examination: Shows megaloblastic reactions
Schilling test is positive

Complication: Gastric carcinoma


Homeopathic medicines for Megaloblastic anemia
Only constitutional remedy can help in this case

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